Jump to content

File:Heterogeneous breast tumor in 3D.jpg

Page contents not supported in other languages.
This is a file from the Wikimedia Commons
From Wikipedia, the free encyclopedia

Original file (2,048 × 2,048 pixels, file size: 1.78 MB, MIME type: image/jpeg)

Summary

Description
English: This is a pre-malignant breast tumor grown from breast cancer cells in a 3D matrix that mimics human breast tissue. The blue represents a nucleus, found in each cell present in the breast tumor. The red fluorescence stain is Vimentin, which is a protein that is heavily produced in invasive tumor cells. The one cell on the left has a lot of Vimentin in it, which might signify that this cell will break away from the tumor and metastasize and form more secondary tumors. The other cells (with less red (i.e. Vimentin) might not. This is striking because this image shows that breast tumors are heterogeneous. Not all cells present in a breast tumor express the same amount of Vimentin. The green stain is Rap1Gap, a tumor suppressor protein used by pre-cancerous cells to prevent the tumor from becoming invasive. Other Information: The image is a 3D reconstruction of 25 z-stacks taken of this tumor structure, taken at 40x magnification with the Zeiss LSM 780 fluorescent microscope. Taken at Wayne State University, Detroit, MI.
Date
Source Own work
Author Sshah74

Licensing

I, the copyright holder of this work, hereby publish it under the following license:
w:en:Creative Commons
attribution
This file is licensed under the Creative Commons Attribution 4.0 International license.
You are free:
  • to share – to copy, distribute and transmit the work
  • to remix – to adapt the work
Under the following conditions:
  • attribution – You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.


Captions

Breast tumors are heterogeneous; one cell can invade and metastasize

Items portrayed in this file

depicts

22 April 2013

image/jpeg

File history

Click on a date/time to view the file as it appeared at that time.

Date/TimeThumbnailDimensionsUserComment
current21:07, 12 December 2019Thumbnail for version as of 21:07, 12 December 20192,048 × 2,048 (1.78 MB)Sshah74User created page with UploadWizard

The following page uses this file:

Metadata