File:SRPFunction2.png
SRPFunction2.png (793 × 436 pixels, file size: 122 KB, MIME type: image/png)
Summary
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The classical function of SRP in translation-translocation. A membrane separates the cytosol from the endoplasmic reticulum. A ribosome (light gray with A, P, and E sites) synthesizes a protein with a signal peptide (green) encoded by messenger RNA (indicated by a line with 5'- and 3-ends). The elongated SRP (blue), with its large (LD) and small (SD) domains, forms a complex which the membrane-resident SRP receptor (SR). When SRP separates, the protein crosses the membrane through a channel or translocon. The signal peptide may be removed by signal peptide peptidase (SP) and the protein modified by oligosaccharyl transferase (OT). |
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| current | 20:14, 31 May 2009 | | 793 × 436 (122 KB) | Czwieb (talk | contribs) | {{Information |Description = |Source = I created this work entirely by myself. |Date = |Author = ~~~ |other_versions = }} |
| 20:01, 31 May 2009 |  | 1,058 × 581 (128 KB) | Czwieb (talk | contribs) | {{Information |Description = |Source = I created this work entirely by myself. |Date = |Author = ~~~ |other_versions = }} | |
| 19:56, 31 May 2009 |  | 5,291 × 2,908 (1.27 MB) | Czwieb (talk | contribs) | {{Information |Description = |Source = I created this work entirely by myself. |Date = |Author = ~~~ |other_versions = }} |
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