Iotalamic acid

Iotalamic acid
Clinical data
Trade names	Conray, Glofil-125, Cysto-Conray II, others
Other names	MI-216, iothalamate meglumine, Iothalamic acid (USAN US)
AHFS/Drugs.com	Consumer Drug Information
License data	US DailyMed: Iothalamate;
Routes of; administration	Intravascular
ATC code	V08AA04 (WHO) ;
Legal status
Legal status	US: ℞-only;
Identifiers
	IUPAC name 3-acetamido-2,4,6-triiodo-5-(methylcarbamoyl)benzoic acid;
CAS Number	2276-90-6;
PubChem CID	3737;
DrugBank	DB09133;
ChemSpider	3606;
UNII	16CHD79MIX;
KEGG	D01258;
ChEBI	CHEBI:31713;
ChEMBL	ChEMBL1201300;
CompTox Dashboard (EPA)	DTXSID5023164 ;
ECHA InfoCard	100.017.181
Chemical and physical data
Formula	C11H9I3N2O4
Molar mass	613.916 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC(=O)NC1=C(C(=C(C(=C1I)C(=O)O)I)C(=O)NC)I;
	InChI InChI=1S/C11H9I3N2O4/c1-3(17)16-9-7(13)4(10(18)15-2)6(12)5(8(9)14)11(19)20/h1-2H3,(H,15,18)(H,16,17)(H,19,20); Key:UXIGWFXRQKWHHA-UHFFFAOYSA-N;

Iotalamic acid, sold under the brand name Conray, is an iodine-containing radiocontrast agent. It is available in form of its salts, sodium iotalamate and meglumine iotalamate. It can be given intravenously or intravesically (into the urinary bladder).^[1]

A radioactive formulation is also available as sodium iothalamate I-125 injection (brand name Glofil-125). It is indicated for evaluation of glomerular filtration in the diagnosis or monitoring of people with kidney disease.^[2]

References

^ ^a ^b ^c "Conray- iothalamate meglumine injection". DailyMed. 1 January 2021. Retrieved 23 February 2022.
^ ^a ^b "Glofil-125- sodium iothalamate i-125 injection injection, solution". DailyMed. 9 December 2019. Retrieved 23 February 2022.
^ "Cysto-Conray II- iothalamate meglumine injection". DailyMed. 31 December 2020. Retrieved 23 February 2022.

External links

"Iothalamate meglumine". Drug Information Portal. U.S. National Library of Medicine.
"Iothalamate sodium". Drug Information Portal. U.S. National Library of Medicine.

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[Conray_FDA_label-1] "Conray- iothalamate meglumine injection". DailyMed. 1 January 2021. Retrieved 23 February 2022.

[Glofil-125_FDA_label-2] "Glofil-125- sodium iothalamate i-125 injection injection, solution". DailyMed. 9 December 2019. Retrieved 23 February 2022.

[Cysto-Conray_II_FDA_label-3] "Cysto-Conray II- iothalamate meglumine injection". DailyMed. 31 December 2020. Retrieved 23 February 2022.

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