N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline
Appearance
(Redirected from N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline)
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Names | |
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Preferred IUPAC name
Ethyl 2-ethoxyquinoline-1(2H)-carboxylate | |
Other names
Ethyl 1,2-dihydro-2-ethoxyquinoline-1-carboxylate
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Identifiers | |
3D model (JSmol)
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Abbreviations | EEDQ |
ECHA InfoCard | 100.036.728 |
PubChem CID
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UNII | |
CompTox Dashboard (EPA)
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Properties | |
C14H17NO3 | |
Molar mass | 247.29 g/mol |
Melting point | 62 to 67 °C (144 to 153 °F; 335 to 340 K) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (EEDQ) is an irreversible dopamine-receptor antagonist.[2]
EEDQ is also a highly specific reagent for carboxyl groups. It enables the coupling of acylamino acids with amino acid esters in high yield and without racemization.[3]
References
[edit]- ^ 2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline at Sigma-Aldrich
- ^ Neuroscience Letters 1992, 137(2), p.265
- ^ https://www.bachem.com/