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Alan McNally

From Wikipedia, the free encyclopedia

Alan McNally is a professor of microbial genomics at the University of Birmingham, UK. He works on the evolutionary genomics and antimicrobial resistance in bacterial pathogens.

Education

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Following undergraduate training at the University of Glasgow (1994-1999), McNally was awarded a PhD in Molecular Microbiology from the Royal (Dick) School of Veterinary Studies, University of Edinburgh, in 2003.[1]

Research

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His laboratory is known for work on:

  • Yersinia species as a model organism for studying bacterial evolution,[2]
  • how bacterial genetic variability can be used to track changes in bacterial populations,[3]
  • how lineages of COVID-19 can vary in their viral load,[4]

He has active collaborations in the UK, China, Germany, France, Vietnam, and the US.[5]

COVID-19 pandemic work

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During the COVID-19 pandemic in the United Kingdom, McNally was seconded to the Milton Keynes Lighthouse Labs as Infectious Disease lead at the Government’s first flagship COVID-19 testing facility. Launched on 9 April 2020, the Milton Keynes Lighthouse Lab was the first of three UK ‘mega-labs’ that vastly increased the testing capacity, allowing many more patient samples to be processed each day.[6]

References

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  1. ^ "Alan McNally". University of Birmingham. Retrieved 10 April 2024.
  2. ^ McNally, Alan; Thomson, Nicholas R.; Reuter, Sandra; Wren, Brendan W. (March 2016). "'Add, stir and reduce': Yersinia spp. as model bacteria for pathogen evolution". Nature Reviews Microbiology. 14 (3): 177–190. doi:10.1038/nrmicro.2015.29. PMID 26876035.
  3. ^ McNally, Alan; Oren, Yaara; Kelly, Darren; Pascoe, Ben; Dunn, Steven; Sreecharan, Tristan; Vehkala, Minna; Välimäki, Niko; Prentice, Michael B.; Ashour, Amgad; Avram, Oren; Pupko, Tal; Dobrindt, Ulrich; Literak, Ivan; Guenther, Sebastian; Schaufler, Katharina; Wieler, Lothar H.; Zhiyong, Zong; Sheppard, Samuel K.; McInerney, James O.; Corander, Jukka (12 September 2016). "Combined Analysis of Variation in Core, Accessory and Regulatory Genome Regions Provides a Super-Resolution View into the Evolution of Bacterial Populations". PLOS Genetics. 12 (9): e1006280. doi:10.1371/journal.pgen.1006280. hdl:10852/53384.
  4. ^ Kidd, Michael; Richter, Alex; Best, Angus; Cumley, Nicola; Mirza, Jeremy; Percival, Benita; Mayhew, Megan; Megram, Oliver; Ashford, Fiona; White, Thomas; Moles-Garcia, Emma; Crawford, Liam; Bosworth, Andrew; Atabani, Sowsan F; Plant, Tim; McNally, Alan (28 May 2021). "S-Variant SARS-CoV-2 Lineage B1.1.7 Is Associated With Significantly Higher Viral Load in Samples Tested by TaqPath Polymerase Chain Reaction". The Journal of Infectious Diseases. 223 (10): 1666–1670. doi:10.1093/infdis/jiab082. PMC 7928763.
  5. ^ "Professor Alan McNally". bsac-conference.com. Retrieved 10 April 2024.
  6. ^ "Alan McNally batonbearers". University of Birmingham. Retrieved 10 April 2024.
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