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Alcohol sulfotransferase

From Wikipedia, the free encyclopedia
Alcohol sulfotransferase
Identifiers
EC no.2.8.2.2
CAS no.9032-76-2
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

Alcohol sulfotransferase is an enzyme that catalyzes the sulfate conjugation of primary and secondary alcohols including many hormones, neurotransmitters, drugs, and xenobiotic compounds.[1][2]

The chemical reaction is:

an alcohol + 3'-phosphoadenylyl-sulfate adenosine 3',5'-bisphosphate + an organosulfate + H+

Family members

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Human genes that encode alcohol sulfotransferases include:

See also

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References

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  1. ^ Lyon ES, Jakoby WB (July 1980). "The identity of alcohol sulfotransferases with hydroxysteroid sulfotransferases". Arch. Biochem. Biophys. 202 (2): 474–81. doi:10.1016/0003-9861(80)90452-X. PMID 6935986.
  2. ^ Lyon ES, Marcus CJ, Wang JL, Jakoby WB (1981). "Hydroxysteroid sulfotransferase". Detoxication and Drug Metabolism: Conjugation and Related Systems. Meth. Enzymol. Vol. 77. pp. 206–13. doi:10.1016/S0076-6879(81)77027-7. ISBN 978-0-12-181977-4. PMID 6173569.
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