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CITED2

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CITED2
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesCITED2, ASD8, MRG-1, MRG1, P35SRJ, VSD2, Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2
External IDsOMIM: 602937; MGI: 1306784; HomoloGene: 4433; GeneCards: CITED2; OMA:CITED2 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_006079
NM_001168388
NM_001168389

NM_010828

RefSeq (protein)

NP_001161860
NP_001161861
NP_006070

NP_034958

Location (UCSC)Chr 6: 139.37 – 139.37 MbChr 10: 17.6 – 17.6 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Cbp/p300-interacting transactivator 2 is a protein that in humans is encoded by the CITED2 gene.[5][6][7]

Interactions

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CITED2 has been shown to interact with EP300,[8][9][10][11] LHX2,[11] TFAP2A,[9][10] and WT1.[12]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000164442Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000039910Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Shioda T, Fenner MH, Isselbacher KJ (Oct 1996). "msg1, a novel melanocyte-specific gene, encodes a nuclear protein and is associated with pigmentation". Proceedings of the National Academy of Sciences of the United States of America. 93 (22): 12298–303. Bibcode:1996PNAS...9312298S. doi:10.1073/pnas.93.22.12298. PMC 37985. PMID 8901575.
  6. ^ Leung MK, Jones T, Michels CL, Livingston DM, Bhattacharya S (Nov 1999). "Molecular cloning and chromosomal localization of the human CITED2 gene encoding p35srj/Mrg1". Genomics. 61 (3): 307–13. doi:10.1006/geno.1999.5970. PMID 10552932.
  7. ^ "Entrez Gene: CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2".
  8. ^ Bhattacharya S, Michels CL, Leung MK, Arany ZP, Kung AL, Livingston DM (Jan 1999). "Functional role of p35srj, a novel p300/CBP binding protein, during transactivation by HIF-1". Genes & Development. 13 (1): 64–75. doi:10.1101/gad.13.1.64. PMC 316375. PMID 9887100.
  9. ^ a b Bragança J, Eloranta JJ, Bamforth SD, Ibbitt JC, Hurst HC, Bhattacharya S (May 2003). "Physical and functional interactions among AP-2 transcription factors, p300/CREB-binding protein, and CITED2". The Journal of Biological Chemistry. 278 (18): 16021–9. doi:10.1074/jbc.M208144200. PMID 12586840.
  10. ^ a b Bragança J, Swingler T, Marques FI, Jones T, Eloranta JJ, Hurst HC, Shioda T, Bhattacharya S (Mar 2002). "Human CREB-binding protein/p300-interacting transactivator with ED-rich tail (CITED) 4, a new member of the CITED family, functions as a co-activator for transcription factor AP-2". The Journal of Biological Chemistry. 277 (10): 8559–65. doi:10.1074/jbc.M110850200. PMID 11744733.
  11. ^ a b Glenn DJ, Maurer RA (Dec 1999). "MRG1 binds to the LIM domain of Lhx2 and may function as a coactivator to stimulate glycoprotein hormone alpha-subunit gene expression". The Journal of Biological Chemistry. 274 (51): 36159–67. doi:10.1074/jbc.274.51.36159. PMID 10593900.
  12. ^ Val P, Martinez-Barbera JP, Swain A (Jun 2007). "Adrenal development is initiated by Cited2 and Wt1 through modulation of Sf-1 dosage". Development. 134 (12): 2349–58. doi:10.1242/dev.004390. PMID 17537799.

Further reading

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