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Draft:METabolic EXplorer

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METabolic EXplorer
Company typePublic
Euronext: METEX
IndustryBiotechnology, Chemicals
FoundedJuly 27, 1999
FounderBenjamin Gonzalez, CEO
Headquarters
Saint Beauzire
,
France
Key people
Benjamin Gonzalez, CEO
Revenue€170 million (2021)
Number of employees
450 (2022)
WebsiteOfficial website

METabolic EXplorer is a company in the field of biotechnology and chemicals, developing and patenting industrial fermentation processes.[1] The company is listed on the Euronext Paris.[2]

History

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Metabolic Explorer was founded in 1999, with an initial public offering on the Paris Stock Exchange in 2007.[3][4][5]

The company's R&D efforts led to the validation by the European Food Safety Authority (EFSA) in 2013 of the safety and efficacy of its biologically sourced L-Methionine in all types of animal feed.[6] In 2016, this L-Methionine production technology was sold for €45 million to the German company Evonik.[7][8]

An exclusive license agreement and partnership were established in 2014 with the South Korean giant SK Chemicals for the production and commercialization of PDO (Propane-1,3-diol),[9][10] which was terminated by both parties in 2015.[11]

In 2018, the company refocused its activities on developing PDO (Propane-1,3-diol) and Butyric acid production at an industrial center in Carling, Moselle, France.[12][13][14]

Activities

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Metabolic Explorer aims to enable industries to continue production despite the anticipated end of oil.

It develops production processes for chemical compounds using microorganisms. These chemical compounds, originally mostly derived from hydrocarbons, are industrially used for manufacturing various products including paints, solvents, bio-based plastics, textile fibers, surgical sutures, animal feed, and more.[15]

The first chemical compounds for which the company has developed biotechnological production processes include:

  • L-Methionine: an essential amino acid used in poultry and piglet feed. Biologically sourced L-Methionine has higher nutritional efficiency compared to chemically sourced D- or DL-Methionine produced from petroleum derivatives.[16][17][18]
  • MPG (Propylene glycol): used as a food additive, non-corrosive antifreeze, in unsaturated polyester resins, paints, solvents, performance liquids, as well as pharmaceutical, hygiene, and cosmetic compounds, among others.[19]
  • PDO (Propane-1,3-diol): a chemical intermediate used in numerous applications from cosmetic or hygiene product formulation, resin and coating production in the construction industry, to polymer production such as PTT or polyurethanes with extensive industrial applications. The company has entered into an agreement with DSM to market PDO in cosmetics under the TILAMAR® PDO with NØØVISTA TM.[14]
  • Glycolic acid: used notably in cleaning products, cosmetics, etc.
  • Butanol: used in various products including paints, coatings, adhesives, solvents.
  • L-Valine: an amino acid used in animal nutrition.[20][21]

METabolic EXplorer is based at the Biopôle Clermont-Limagne in Saint-Beauzire, Auvergne, France.[22]

Its two production subsidiaries are based in France: METEX NØØVISTA in Carling Saint-Avold (Grand Est) and METEX NØØVISTAGO in Amiens (Hauts-de-France). The group also has offices in Paris.[23]

References

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  1. ^ "Metabolic Explorer Granted Patent for the production of Propylene Glycol". Drug Discovery from Technology Networks. Retrieved 2024-04-29.
  2. ^ "METABOLIC EXPLORER". live.euronext.com. Retrieved 2024-04-26.
  3. ^ "Metabolic Explorer réussit son entrée en Bourse". lesechos.fr. 2007-04-12. Archived from the original on 2018-05-17. Retrieved 2024-04-29.
  4. ^ "Successful IPO for METabolic EXplorer Fruitful Partnership between Venture Capital and a Talented Start-up". Omnes Capital. Retrieved 2024-04-29.
  5. ^ "METabolic EXplorer". Omnes Capital. Retrieved 2024-04-29.
  6. ^ EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) (2013-10-29). "Scientific Opinion on the safety and efficacy of L-methionine produced by Escherichia coli (KCCM 11252P) and Escherichia coli (KCCM 11340P) for all animal species". EFSA Journal. 11 (10). doi:10.2903/j.efsa.2013.3428.
  7. ^ Corric, Par Johann (2016-11-29). "Metabolic Explorer vend sa L-Methionine pour 45 millions d'euros". lerevenu.com. Archived from the original on 2018-02-03. Retrieved 2024-04-29.
  8. ^ "Evonik Buys Metabolic's Methionine Portfolio | CHEManager". www.chemanager-online.com. Retrieved 2024-04-29.
  9. ^ "METabolic EXplorer et SK CHEMICALS Co. Ltd. : signature d'un accord exclusif pour la production et la commercialisation de PDO". euronext.com. 2014-06-01. Archived from the original on 2016-03-03.
  10. ^ "Metabolic Explorer SA". reuters.com. Retrieved 2024-04-29.
  11. ^ Corric, Par Johann (2015-11-09). "Metabolic Explorer : fin de l'accord avec SK Chemicals | Le Revenu". lerevenu.com. Archived from the original on 2018-07-04. Retrieved 2024-04-29.
  12. ^ "METabolic EXplorer, Focalisation des ressources R&D en support du projet PDO/AB de Carling – METabolic EXplorer". metabolic-explorer.fr. 2018-03-22. Archived from the original on 2022-03-31. Retrieved 2024-04-29.
  13. ^ Bohlinger, Philippe (2018-04-11). "A Carling, METabolic EXplorer va injecter 37 millions d'euros dans une unité de biochimie industrielle". L'Usine Nouvelle (in French).
  14. ^ a b "METABOLIC EXPLORER". Actusnews Wire. Retrieved 2024-04-29.
  15. ^ "green chemistry France". metabolic-explorer.com. Archived from the original on 2016-02-26. Retrieved 2024-04-29.
  16. ^ "ProQuest Document View - Functional Role and Application of Tryptophan and Methionine in Animals". gradworks.umi.com. Archived from the original on 2015-06-29. Retrieved 2024-04-29.
  17. ^ Shen, Y. B.; Weaver, A. C.; Kim, S. W. (2014-12-01). "Effect of feed grade L-methionine on growth performance and gut health in nursery pigs compared with conventional DL-methionine". Journal of Animal Science. 92 (12): 5530–5539. doi:10.2527/jas.2014-7830. ISSN 0021-8812. PMID 25414105.
  18. ^ "Comparative efficacy of L-methionine and DL-methionine in piglets". agris.fao.org. Archived from the original on 2015-06-30. Retrieved 2024-04-29.
  19. ^ "Signature d'un accord entre METabolic EXplorer et UPM pour le développement d'un procédé de fabrication de MPG à partir de sucres cellulosiques de deuxième génération" (PDF). metabolic-explorer.com. 2015-06-11. Archived from the original (PDF) on 2015-06-30.
  20. ^ "Metex met au point un second procédé de fermentation | Formule Verte". formule-verte.com. 2021-12-05. Archived from the original on 2021-12-09. Retrieved 2024-04-29.
  21. ^ "Evonik adds L-valine to its amino acid portfolio for animal nutrition - Evonik Industries". animal-nutrition.evonik.com. Retrieved 2024-04-29.
  22. ^ "METABOLIC EXPLORER". Biopôle Clermont-Limagne. Retrieved 2024-04-29.
  23. ^ "Contact". METabolic EXplorer. Retrieved 2024-04-29.
[edit]

Official website

Category:Chemical companies of France Category:Companies listed on Euronext Paris Category:Biotechnology companies of France Category:Companies established in 1999

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