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Fanetizole

From Wikipedia, the free encyclopedia
Fanetizole
Pharmacokinetic data
Protein binding%
Identifiers
  • 4-Phenyl-N-(2-phenylethyl)-1,3-thiazol-2-amine
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC17H16N2S
Molar mass280.39 g·mol−1
3D model (JSmol)
  • n1c(csc1NCCc2ccccc2)c3ccccc3
  • InChI=1S/C17H16N2S/c1-3-7-14(8-4-1)11-12-18-17-19-16(13-20-17)15-9-5-2-6-10-15/h1-10,13H,11-12H2,(H,18,19)
  • Key:WEEYMMXMBFJUAI-UHFFFAOYSA-N
  (verify)

Fanetizole is a drug that has immunoregulating activity.[citation needed]

Synthesis

[edit]

Reaction of β-phenethylamine with ammonium thiocyanate gives the thiourea (2). Treatment of that product with phenacyl bromide produces fanetizole (3).[1]

Fanetizole synthesis

References

[edit]
  1. ^ Lombardino, J. G.; 1981, U.S. patent 4,307,106