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Ferric-chelate reductase (NADPH)

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Ferric-chelate reductase (NADPH)
Identifiers
EC no.1.16.1.9
CAS no.120720-17-4
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Ferric-chelate reductase (NADPH) (EC 1.16.1.9, ferric chelate reductase, iron chelate reductase, NADPH:Fe3+-EDTA reductase, NADPH-dependent ferric reductase, yqjH (gene)) is an enzyme with systematic name Fe(II):NADP+ oxidoreductase.[1][2][3] This enzyme catalyses the following chemical reaction

2 Fe(II) + 2 apo-siderophore + NADP+ + H+ 2 Fe(III)-siderophore + NADPH

Ferric-chelate reductase contains FAD.

See also

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References

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  1. ^ Bamford VA, Armour M, Mitchell SA, Cartron M, Andrews SC, Watson KA (September 2008). "Preliminary X-ray diffraction analysis of YqjH from Escherichia coli: a putative cytoplasmic ferri-siderophore reductase". Acta Crystallographica Section F. 64 (Pt 9): 792–6. doi:10.1107/S174430910802352X. PMC 2531270. PMID 18765906.
  2. ^ Wang S, Wu Y, Outten FW (January 2011). "Fur and the novel regulator YqjI control transcription of the ferric reductase gene yqjH in Escherichia coli". Journal of Bacteriology. 193 (2): 563–74. doi:10.1128/JB.01062-10. PMC 3019823. PMID 21097627.
  3. ^ Miethke M, Hou J, Marahiel MA (December 2011). "The siderophore-interacting protein YqjH acts as a ferric reductase in different iron assimilation pathways of Escherichia coli". Biochemistry. 50 (50): 10951–64. doi:10.1021/bi201517h. PMID 22098718.
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