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Hilário de Gouvêa

From Wikipedia, the free encyclopedia
Dr. Hilario Soares de Gouvêa
Hilario de Gouvêa in 1869
Born1843 (1843)
Brazil
Died1929 (aged 85–86)
Known forfirst documentation of hereditary cancer
Scientific career
FieldsOphthalmology, Oncology
Hilário de Gouveia

Hilário de Gouvêa (1843-1929) was a Brazilian ophthalmologist noted for being the first person to document a case of hereditary cancer.[1] The cause of the recessive familial retinoblastoma he described was later further investigated and resulted in the first reported example of a tumor suppressor gene, RB.

References

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  1. ^ Monteiro, Alvaro N.A.; Waizbort, Ricardo (2007-05-30). "The accidental cancer geneticist: Hilário de Gouvêa and hereditary retinoblastoma". Cancer Biology & Therapy. 6 (5): 811–813. doi:10.4161/cbt.6.5.4420. ISSN 1538-4047. PMID 17592249. S2CID 23841904.