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List of Coronavirus live isolates

From Wikipedia, the free encyclopedia

This article aims at keeping an up-to-date list of Coronavirus strains and subspecies successfully isolated and cultured in laboratory, a task which is often challenging. When relevant it shall include a few synthetic chimera as well as some strains that were only propagated in laboratory animals.

Alphacoronavirus

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Tegacovirus

[edit]
  • TGEV [10] PRCV [11]
  • Feline coronavirus
  • Canine coronavirus.[12]
  • A recent recombinant CCoV-HuPn-2018 [13] including a human case [14]

Betacoronavirus

[edit]

Merbecovirus

[edit]
  • HKU5 SARS-S chimera [15]
  • HKU5 and a MERS PDF-2180-S chimera, with trypsin [16]
  • Various MERS HKU4-RBD chimera [17]
  • HKU4 [18]
  • MERS [19]
  • HKU4-like Pangolin Coronavirus [20][21]

Embecovirus

[edit]
  • Bovine coronavirus [22]
  • Rabbit HKU14 [23]
  • MHV
  • OC43 (1967)
  • HKU1 [24]
  • Parker rat coronavirus [25]
  • Dromedary camel HKU23 [26]
  • Canine respiratory coronavirus (CRCoV) [27]
  • Equine coronavirus [28]

Sarbecovirus

[edit]
  • SARS [29]
  • HKU3 SARS-RBD synthetic recombinant [30]
  • bat-SL-CoV ZC45 (in suckling rats) [31]
  • WIV1 [32]
  • RsSHC014 (synthetic clone) [33]
  • WIV16 [34]
  • WIV1 Rs4874-S synthetic chimera [35]
  • Rs4874 and two synthetic chimera WIV1 Rs7237-S and WIV1 Rs4231-S [36]
  • SARS-CoV-2 [37]
  • BANAL-236 [38]
  • Pangolin Guangxi P2V [39][40]
  • Rco319, Rc-os20, Rc-mk2, Rc-kw8 (in Vero with Rc-ACE2)[41]
  • WIV1 Rs4081-S synthetic chimera (with trypsin). In the spike it is a member of clade 2 (including HKU3).[42]
  • WIV1 RsSHC014-S1 chimera[43]
  • Two clade 1 viruses (using ACE2) RsYN2012 and RsYN2016 and one clade 2 virus (not using ACE2) RsHuB2019 in Huh7 cells with trypsin.[44]
  • pangolin/Guangdong, in Vero cells, human organoids, hACE2 mice, hamsters [45][46]

Gammacoronavirus

[edit]
  • Avian coronavirus (IBV) [47]
  • Turkey coronavirus[48]

Deltacoronavirus

[edit]
  • Porcine deltacoronavirus HKU15[49] including a human case [50]
  • Parrot coronavirus [51]

References

[edit]
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