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MAPKAP1

From Wikipedia, the free encyclopedia

MAPKAP1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesMAPKAP1, JC310, MIP1, SIN1, SIN1b, SIN1g, mitogen-activated protein kinase associated protein 1, MAPK associated protein 1
External IDsOMIM: 610558; MGI: 2444554; HomoloGene: 11473; GeneCards: MAPKAP1; OMA:MAPKAP1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)
RefSeq (protein)
Location (UCSC)Chr 9: 125.44 – 125.71 MbChr 2: 34.41 – 34.62 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Target of rapamycin complex 2 subunit MAPKAP1 is a protein that in humans is encoded by the MAPKAP1 gene.[5][6] As the name indicates, it is a subunit of mTOR complex 2.

This gene encodes a protein that is highly similar to the yeast SIN1 protein, a stress-activated protein kinase. Alternatively spliced transcript variants encoding distinct isoforms have been described. Alternate polyadenylation sites as well as alternate 3' UTRs have been identified for transcripts of this gene.[6]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000119487Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000038696Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Schroder W, Cloonan N, Bushell G, et al. (Sep 2004). "Alternative polyadenylation and splicing of mRNAs transcribed from the human Sin1 gene". Gene. 339: 17–23. doi:10.1016/j.gene.2004.07.001. PMID 15363842.
  6. ^ a b "Entrez Gene: MAPKAP1 mitogen-activated protein kinase associated protein 1".

Further reading

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