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Memantine/donepezil

From Wikipedia, the free encyclopedia

Memantine/donepezil
Combination of
MemantineNMDA receptor antagonist
DonepezilAcetylcholinesterase inhibitor
Clinical data
Trade namesNamzaric
AHFS/Drugs.comMicromedex Detailed Consumer Information
License data
Routes of
administration
By mouth
ATC code
Legal status
Legal status
Identifiers
KEGG

Memantine/donepezil, sold under the brand name Namzaric among others, is a fixed dose combination medication used for the treatment of dementia of the Alzheimer's type.[1] It contains memantine, as the hydrochloride, a NMDA receptor antagonist; and donepezil as the hydrochloride, an acetylcholinesterase inhibitor.[1] It is taken by mouth.[1]

Memantine/donepezil was approved for medical use in the United States in 2014.[3]

References

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  1. ^ a b c d "Namzaric- memantine hydrochloride and donepezil hydrochloride capsule; Namzaric- memantine hydrochloride and donepezil hydrochloride kit". DailyMed. 22 January 2019. Archived from the original on 20 January 2022. Retrieved 22 December 2023.
  2. ^ "Periodic safety update report single assessment donepezil / memantine". European Medicines Agency. 7 March 2024. Retrieved 2 May 2024.
  3. ^ "Namzaric (memantine hydrochloride extended-release/donepezil hydrochloride) Capsules". U.S. Food and Drug Administration (FDA). 13 May 2015. Archived from the original on 22 December 2023. Retrieved 22 December 2023.

Further reading

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