Jump to content

PABPC5

From Wikipedia, the free encyclopedia
PABPC5
Identifiers
AliasesPABPC5, PABP5, poly(A) binding protein cytoplasmic 5
External IDsOMIM: 300407; MGI: 2136401; HomoloGene: 5857; GeneCards: PABPC5; OMA:PABPC5 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_080832

NM_053114

RefSeq (protein)

NP_543022

NP_444344

Location (UCSC)Chr X: 91.43 – 91.44 MbChr X: 118.84 – 118.84 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Poly(A) binding protein cytoplasmic 5 is a protein that in humans is encoded by the PABPC5 gene. [5]

Function

[edit]

This gene encodes a poly(A)-binding protein that binds to the polyA tail found at the 3' end of most eukaryotic mRNAs. It is thought to play a role in the regulation of mRNA metabolic processes in the cytoplasm. This gene is located in a gene-poor region within the X-specific 13d-sY43 subinterval of the chromosome Xq21.3/Yp11.2 homology block. It is located close to translocation breakpoints associated with premature ovarian failure, and is therefore a potential candidate gene for this disorder. [provided by RefSeq, May 2010].

References

[edit]
  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000174740Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000034732Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Poly(A) binding protein cytoplasmic 5". Retrieved 2020-04-16.

Further reading

[edit]


This article incorporates text from the United States National Library of Medicine, which is in the public domain.