PARVG

PARVG
Identifiers
Aliases	PARVG, parvin gamma
External IDs	OMIM: 608122; MGI: 2158329; HomoloGene: 11151; GeneCards: PARVG; OMA:PARVG - orthologs
Gene location (Human)
Chr.	Chromosome 22 (human)
End	44,219,533 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	84,227,179 bp
RNA expression pattern
	Top expressed in
	granulocyte; ; monocyte; ; spleen; ; blood; ; appendix; ; lymph node; ; bone marrow; ; bone marrow cells; ; upper lobe of left lung; ; right lung;
	Top expressed in
	granulocyte; ; thymus; ; spleen; ; tibiofemoral joint; ; mesenteric lymph nodes; ; bone marrow; ; dentate gyrus of hippocampal formation granule cell; ; spermatid; ; blood; ; lumbar subsegment of spinal cord;
	More reference expression data
	n/a
Gene ontology
Molecular function	actin binding; protein binding;
Cellular component	cytoplasm; cell junction; plasma membrane; cytoskeleton; membrane; focal adhesion; actin cytoskeleton;
Biological process	actin cytoskeleton reorganization; cell-matrix adhesion; cell adhesion; establishment or maintenance of cell polarity; cell projection assembly; substrate adhesion-dependent cell spreading;
	Sources:Amigo / QuickGO
Orthologs
	64098
	64099
	ENSG00000138964
	ENSMUSG00000022439
	Q9HBI0
	Q9ERD8
NM_001137605; NM_001137606; NM_001254741; NM_001254742; NM_001254743;
	NM_022141
	NM_001162500; NM_022321
	NP_001131077; NP_071424
	NP_001155972; NP_071716
	Wikidata
View/Edit Human	View/Edit Mouse

Gamma-parvin is a protein that in humans is encoded by the PARVG gene.^[5]^[6]

Members of the parvin family, including PARVG, PARVA and PARVB, are actin-binding proteins associated with focal contacts.[supplied by OMIM]^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000138964 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000022439 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Olski TM, Noegel AA, Korenbaum E (Feb 2001). "Parvin, a 42 kDa focal adhesion protein, related to the alpha-actinin superfamily". J Cell Sci. 114 (Pt 3): 525–38. doi:10.1242/jcs.114.3.525. PMID 11171322.
^ ^a ^b "Entrez Gene: PARVG parvin, gamma".

Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Dunham I, Shimizu N, Roe BA, et al. (1999). "The DNA sequence of human chromosome 22" (PDF). Nature. 402 (6761): 489–95. Bibcode:1999Natur.402..489D. doi:10.1038/990031. PMID 10591208.
Korenbaum E, Olski TM, Noegel AA (2002). "Genomic organization and expression profile of the parvin family of focal adhesion proteins in mice and humans". Gene. 279 (1): 69–79. doi:10.1016/S0378-1119(01)00743-0. PMID 11722847.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Collins JE, Goward ME, Cole CG, et al. (2003). "Reevaluating human gene annotation: a second-generation analysis of chromosome 22". Genome Res. 13 (1): 27–36. doi:10.1101/gr.695703. PMC 430954. PMID 12529303.
Collins JE, Wright CL, Edwards CA, et al. (2005). "A genome annotation-driven approach to cloning the human ORFeome". Genome Biol. 5 (10): R84. doi:10.1186/gb-2004-5-10-r84. PMC 545604. PMID 15461802.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Alonso ME, Bello MJ, de Campos JM, et al. (2005). "No evidence of INI1hSNF5 (SMARCB1) and PARVG point mutations in oligodendroglial neoplasms". Cancer Genet. Cytogenet. 160 (2): 169–73. doi:10.1016/j.cancergencyto.2004.12.020. PMID 15993274.
Yoshimi R, Yamaji S, Suzuki A, et al. (2006). "The gamma-parvin-integrin-linked kinase complex is critically involved in leukocyte-substrate interaction". J. Immunol. 176 (6): 3611–24. doi:10.4049/jimmunol.176.6.3611. PMID 16517730.

This article on a gene on human chromosome 22 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000138964 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000022439 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11171322-5] Olski TM, Noegel AA, Korenbaum E (Feb 2001). "Parvin, a 42 kDa focal adhesion protein, related to the alpha-actinin superfamily". J Cell Sci. 114 (Pt 3): 525–38. doi:10.1242/jcs.114.3.525. PMID 11171322.

[entrez-6] "Entrez Gene: PARVG parvin, gamma".

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References

Further reading