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SCAMP1

From Wikipedia, the free encyclopedia
SCAMP1
Identifiers
AliasesSCAMP1, SCAMP, SCAMP37, secretory carrier membrane protein 1
External IDsOMIM: 606911; MGI: 1349480; HomoloGene: 37975; GeneCards: SCAMP1; OMA:SCAMP1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001290229
NM_004866
NM_052822

NM_029153
NM_001346609

RefSeq (protein)

NP_001277158
NP_004857

NP_001333538
NP_083429

Location (UCSC)Chr 5: 78.36 – 78.48 MbChr 13: 94.34 – 94.42 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Secretory carrier-associated membrane protein 1 is a protein that in humans is encoded by the SCAMP1 gene.[5][6]

Function

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This gene product belongs to the SCAMP family of proteins which are secretory carrier membrane proteins. They function as carriers to the cell surface in post-golgi recycling pathways. Different family members are highly related products of distinct genes, and are usually expressed together. These findings suggest that the SCAMPs may function at the same site during vesicular transport rather than in separate pathways.[6]

Interactions

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SCAMP1 has been shown to interact with ITSN1[7] and AP1GBP1.[7]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000085365Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000021687Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Singleton DR, Wu TT, Castle JD (September 1997). "Three mammalian SCAMPs (secretory carrier membrane proteins) are highly related products of distinct genes having similar subcellular distributions". Journal of Cell Science. 110. 110 ( Pt 17) (17): 2099–107. doi:10.1242/jcs.110.17.2099. PMID 9378760.
  6. ^ a b "Entrez Gene: SCAMP1 secretory carrier membrane protein 1".
  7. ^ a b Fernández-Chacón R, Achiriloaie M, Janz R, Albanesi JP, Südhof TC (April 2000). "SCAMP1 function in endocytosis". The Journal of Biological Chemistry. 275 (17): 12752–6. doi:10.1074/jbc.275.17.12752. PMID 10777571.

Further reading

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