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Set domain containing 1b

From Wikipedia, the free encyclopedia
SETD1B
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesSETD1B, KMT2G, Set1B, SET domain containing 1B, SET domain containing 1B, histone lysine methyltransferase, IDDSELD
External IDsOMIM: 611055; MGI: 2652820; HomoloGene: 137311; GeneCards: SETD1B; OMA:SETD1B - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_015048
NM_001353345

NM_001040398
NM_177581

RefSeq (protein)

NP_001340274

NP_001035488

Location (UCSC)Chr 12: 121.8 – 121.83 MbChr 5: 123.28 – 123.31 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

SET domain containing 1B is a protein that in humans is encoded by the SETD1B gene. [5]

Function

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SET1B is a component of a histone methyltransferase complex that produces trimethylated histone H3 at Lys4 (Lee et al., 2007 [PubMed 17355966]).[supplied by OMIM, Mar 2008].

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000139718Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000038384Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: SET domain containing 1B". Retrieved 2018-01-13.

Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.