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Small nucleolar RNA SNORD21

From Wikipedia, the free encyclopedia
Small nucleolar RNA SNORD21
Identifiers
SymbolSNORD21
Alt. SymbolsU21
RfamRF00068
Other data
RNA typeGene; snRNA; snoRNA; CD-box
Domain(s)Eukaryota
GOGO:0006396 GO:0005730
SOSO:0000593
PDB structuresPDBe

In molecular biology, U21 is a member of the C/D class of snoRNA which contain the C (UGAUGA) and D (CUGA) box motifs. U21 is encoded within an intron of the gene for ribosomal protein L5 in mammals,[1] but within introns of the ADP ribosylation factor gene in Drosophila.[2] U21 snoRNA has a 13 nucleotide region of complementarity with an invariant region of eukaryotic 28S ribosomal RNA.

References

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  1. ^ Qu LH, Nicoloso M, Michot B, Azum MC, Caizergues-Ferrer M, Renalier MH, Bachellerie JP (October 1994). "U21, a novel small nucleolar RNA with a 13 nt. complementarity to 28S rRNA, is encoded in an intron of ribosomal protein L5 gene in chicken and mammals". Nucleic Acids Research. 22 (20): 4073–81. doi:10.1093/nar/22.20.4073. PMC 331892. PMID 7937132.
  2. ^ Renalier MH, Nicoloso M, Qu LH, Bachellerie JP (February 1996). "SnoRNA U21 is also intron-encoded in Drosophila melanogaster but in a different host-gene as compared to warm-blooded vertebrates". FEBS Letters. 379 (3): 212–6. doi:10.1016/0014-5793(95)01511-6. PMID 8603691. S2CID 28632486.
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