Talk:Gardner's syndrome
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[edit]Feel that Gardner's syndrome's merge with FAP should be made more clear in the introduction? It really isn't a distinct medical category any more. — Preceding unsigned comment added by 129.67.46.169 (talk) 15:23, 15 January 2016 (UTC)
Agree
[edit]I couldn't put this better than the author of a recently published paper:
"A variety of terms have been used to describe individuals with an APC-associated polyposis condition; FAP, attenuated FAP, Gardner syndrome, Turcot syndrome, or the recently described gastric adenocarcinoma and proximal polyposis of the stomach (GAPPS). The clinical features associated with these phenotypes are included here; however, all are now genetically defined as caused by pathogenic variants in APC. Terms such as Gardner syndrome and Turcot syndrome are of historical interest and should not be used any longer as both are now known to be part of the FAP spectrum. GAPPS was only recently described and the current phenotype is not yet well understood. Management guidelines differ between FAP and attenuated FAP. A consensus has not been reached regarding the precise clinical diagnostic criteria that distinguish FAP from attenuated FAP"[1] Tmbirkhead (talk) 20:06, 20 September 2018 (UTC)
Merge with Familial Adenomatous Polyposis
[edit]This article should either be made more clear in the first paragraph or merged with FAP, and listed as an historical subtype. Tmbirkhead (talk) 20:08, 20 September 2018 (UTC)
References
- ^ Jasperson, Kory W.; Patel, Swati G.; Ahnen, Dennis J. (1993), Adam, Margaret P.; Ardinger, Holly H.; Pagon, Roberta A.; Wallace, Stephanie E. (eds.), "APC-Associated Polyposis Conditions", GeneReviews®, University of Washington, Seattle, PMID 20301519, retrieved 2018-09-20
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