Talk:Lipid-anchored protein

Wiki Education Foundation-supported course assignment

This article is or was the subject of a Wiki Education Foundation-supported course assignment. Further details are available on the course page. Student editor(s): Abbey311.

Above undated message substituted from Template:Dashboard.wikiedu.org assignment by PrimeBOT (talk) 02:39, 17 January 2022 (UTC)

Proposed Changes

Below is an outline of some of the changes I plan to make for this article. It’s going to be my first time making real big changes to an article so I would appreciate any tips and advice!

Outline

• Compile a better phrased definition of lipid-anchored proteins
  • Include aka lipid-linked proteins
  • Include their location
  • Possibly include an image

• Three types of lipid-anchored proteins:
  • Prenylated proteins
  • Fatty acylated proteins
  • Glycosylphosphatidylinositol-linked proteins (GPI)

• Prenylated proteins
  • Structure
  • Isoprene units
  • Common isporenoid groups
  • Site of attachment
  • Picture

• Fatty acylated proteins
  • Structure
  • Myristic acid & location
  • Palmitic acid & location
  • Sites of attachment
  • Picture

• GPI proteins
  • Structure
  • Location
  • Site of attachment
  • Picture

• Lipid-protein interactions in membrane
  • Protein-protein interactions
  • Structure and function modification

I basically plan to include more detail on the different types of lipid-anchored proteins. With each type I plan to talk about its structure, location, site of attachment, (where the lipid usually binds on the protein), some specific examples and to include a picture. I also plan to talk about how the lipid attached to the protein might change the proteins structure and function and how that might contribute to the overall interactions with other protein on the membrane. I’m still researching this last part so any relevant articles or websites would be appreciated! Abbey311 (talk) 01:53, 3 November 2015 (UTC)

CAAX motif

The main article says what amino acids are important for the last part (X); but only 5 aminoacids are described or so. Right now I am looking at Isoleucine (I) via ProSite, in the mouse GTPase ARHJ, and wikipedia does not say that Isoleucine means e.g. when we have CAAI or CAII. I may probably find out eventually, but right now I don't know, so I add this here in the event that somebody else knows, and can extend that part of the wikipedia entry. And perhaps also explain why not every aminoacid seems to be important there, e. g. why only these ~6 aminoacids are at position X. 131.130.83.43 (talk) 10:01, 28 April 2016 (UTC)

Basic information lacking; language

Hello, dear (scientific) writers,

for laypersons this article lacks the basic information of what you are talking about ;-) —where are those membranes, cells, lipids?— in plants, animals, only mammals like humans, only primates, or in every living thing?

Also, like increasingly many pages here it would, I think, fit better into Wikipedia's definition if it was written in a way more distant to university papers' experts-only language and more easily understandable for common readers, who come from many fields and may be highly qualified in their own fields, but rightly expect not to have to become professionals and read scientific-study-lingo in Wikipedia when trying to get some basic information in fields different from their own.

Such people CAN absolutely obtain in-depth-knowledge from specialist literature, but they, as well as less educated persons, do not or SHOULD not come to Wikipedia for this, but (should) here expect to get explanations in more everyday terms. When specialist terms are inevitable they should be explained in everyday words. All in all in writing about a topic it should be considered that people can have come to that article from anywhere, not only from another already completely understood insider-knowledge-page very closely related to the topic.

Please do not take this the wrong way, dear writers, I appreciate your labour and that you put the topic here at all, but... -->see what I said above :-)

Thanks to everybody contributing. Would be great if this (as it seems to me) increasing problem would/ could be tackled.

2A02:3033:402:FC54:1:0:581A:C5FE (talk) 08:22, 8 September 2022 (UTC)