Talk:MHC class II
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[edit]"MHC (major histocompatibility complex) Class II molecules are found only on a two specialized cell types, including macrophages, dendritic cells and B cells, all of which are professional antigen-presenting cells (APCs)."
I suggest to remove "only on two". Is it really found only on two cell types (since three are mentionned)? Also, MHC class II could be found on endothelial cells in the Central Nervous System (CNS) (see: Witwer KW et al, PLoS ONE 4(12):e8129, 2009, doi:10.1371/journal.pone.0008129). --Corpshumain (talk) 17:09, 11 March 2010 (UTC)
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destruction of part of a cell or eliminating a gene from the secence of a cell.
[edit]can you eliminate gene secence without changing the function of a cell. Example MHC class 11 can it be eliminated from the cellular make up of the T cell without changing the function of the cell? my understanding is that a few structures of the T cell is really not needed in opinion it does more harm than good like the kinisos process it changes the cell intarally. could this change awaken dormined cancerious cells etc. —Preceding unsigned comment added by Taylor's theory (talk • contribs) 11:38, 4 July 2010 (UTC)
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Addition of a section on MHC II deficiency
[edit]Bibliography: Roifman, C., & Grunebaum, E. (n.d.). Primary T-cell Immunodeficiencies . In Clinical Immunology (4th ed., pp. 437-453). doi:https://doi.org/10.1016/B978-0-7234-3691-1.00052-0
Delves, P. J., & Roitt, I. M. (1998). Encyclopedia of immunology. London: Academic Press.
Mak, T. W., & Saunders, M. E. (2006). The immune response: basic and clinical principles ;. Amsterdam: Elsevier Acad. Press.
Advances in Immunology (Vol. 136). (2016). Academic Pr.
Steimle, V., Otten, L., Zufferey, M., & Mach, B. (n.d.). Complementation cloning of an MHC class II transactivator mutated in hereditary MHC class II deficiency (or bare lymphocyte syndrome). In Cell (1st ed., Vol. 75, pp. 135-146). doi:https://doi.org/10.1016/S0092-8674(05)80090-X
Immcarle62 (talk) 02:05, 29 January 2018 (UTC) Immcarle62
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