Template:1910 American League standings
| Team | W | L | Pct. | GB | Home | Road |
|---|---|---|---|---|---|---|
| Philadelphia Athletics | 102 | 48 | .680 | — | 57–19 | 45–29 |
| New York Highlanders | 88 | 63 | .583 | 14½ | 49–25 | 39–38 |
| Detroit Tigers | 86 | 68 | .558 | 18 | 46–31 | 40–37 |
| Boston Red Sox | 81 | 72 | .529 | 22½ | 51–28 | 30–44 |
| Cleveland Naps | 71 | 81 | .467 | 32 | 39–36 | 32–45 |
| Chicago White Sox | 68 | 85 | .444 | 35½ | 41–37 | 27–48 |
| Washington Senators | 66 | 85 | .437 | 36½ | 38–35 | 28–50 |
| St. Louis Browns | 47 | 107 | .305 | 57 | 26–51 | 21–56 |