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Template:Pharmacological properties of major anabolic steroids

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Pharmacological properties of major anabolic steroids
Compound Class 5α-R AROM 3-HSD AAR Estr Prog Oral HepatTooltip Hepatotoxicity
Androstanolone DHT + *
Boldenone T ± ** ±
Drostanolone DHT ***
Ethylestrenol 19-NT; 17α-A + () ± *** + + + +
Fluoxymesterone T; 17α-A + () * + +
Mestanolone DHT; 17α-A + * + +
Mesterolone DHT + * ±
Metandienone T; 17α-A ± ** + + +
Metenolone DHT ** ±
Methyltestosterone T; 17α-A + () + * + + +
Nandrolone 19-NT + () ± *** ± +
Norethandrolone 19-NT; 17α-A + () ± *** + + + +
Oxandrolone DHT; 17α-A *** + ±
Oxymetholone DHT; 17α-A *** + + +
Stanozolol DHT; 17α-A *** + +
Testosterone T + () + * + ±a
Trenbolone 19-NT *** +
Key: + = Yes. ± = Low. = No. = Potentiated. = Inactivated. *** = High. ** = Moderate. * = Low. Abbreviations: 5α-R = Metabolized by 5α-reductase. AROM = Metabolized by aromatase. 3-HSD = Metabolized by 3α-Tooltip 3α-hydroxysteroid dehydrogenase and/or 3β-HSDTooltip 3β-hydroxysteroid dehydrogenase. AAR = Anabolic-to-androgenic ratio (amount of anabolic (myotrophic) effect relative to androgenic effect). Estr = Estrogenic. Prog = Progestogenic. Oral = Oral activity. Hepat = Hepatotoxicity. Footnotes: a = As testosterone undecanoate. Sources: [1][2][3]

References

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  1. ^ Llewellyn, William (2011). Anabolics. Molecular Nutrition Llc. pp. 533–, 402–412, 460–467. ISBN 978-0-9828280-1-4.
  2. ^ Kicman, A T (2008). "Pharmacology of anabolic steroids". British Journal of Pharmacology. 154 (3): 502–521. doi:10.1038/bjp.2008.165. PMC 2439524. PMID 18500378.
  3. ^ Schänzer W (1996). "Metabolism of anabolic androgenic steroids" (PDF). Clin. Chem. 42 (7): 1001–20. doi:10.1093/clinchem/42.7.1001. PMID 8674183.