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Voltage-gated potassium-channel Kv1.4 IRES

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Voltage-gated potassium-channel Kv1.4 IRES
Predicted secondary structure and sequence conservation of IRES_Kv1_4
Identifiers
SymbolIRES_Kv1_4
RfamRF00447
Other data
RNA typeCis-reg; IRES
Domain(s)Eukaryota
GOGO:0043022
SOSO:0000243
PDB structuresPDBe

This family represents the Kv1.4 voltage-gated potassium channel internal ribosome entry site (IRES). This region has been shown to mediate internal ribosome entry in cells derived from brain, heart, and skeletal muscle; tissues known to express Kv1.4 mRNA species.[1]

References

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  1. ^ Jang GM, Leong LE, Hoang LT, Wang PH, Gutman GA, Semler BL (November 2004). "Structurally distinct elements mediate internal ribosome entry within the 5'-noncoding region of a voltage-gated potassium channel mRNA". The Journal of Biological Chemistry. 279 (46): 47419–47430. doi:10.1074/jbc.M405885200. PMID 15339906.
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