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ELF1

From Wikipedia, the free encyclopedia
ELF1
Identifiers
AliasesELF1, E74 like ETS transcription factor 1, EFTUD1, RIA1
External IDsOMIM: 189973; MGI: 107180; HomoloGene: 7303; GeneCards: ELF1; OMA:ELF1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001286411
NM_001286412
NM_007920

RefSeq (protein)

NP_001273340
NP_001273341
NP_031946

Location (UCSC)Chr 13: 40.93 – 41.06 MbChr 14: 79.72 – 79.82 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

E74-like factor 1 (ets domain transcription factor) is a protein that in humans is encoded by the ELF1 gene.[5]

Function

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This gene encodes an E26 transformation-specific related transcription factor. The encoded protein is primarily expressed in lymphoid cells and can act as both an enhancer and a repressor to regulate transcription of various genes. Alternative splicing results in multiple transcript variants.[5]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000120690Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000036461Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b "Entrez Gene: E74-like factor 1 (ets domain transcription factor)".

Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.